The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
8410993 |
24 |
Mammalian topoisomerase II inhibitory activity of 1-cyclopropyl-6,8- difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarb oxylic acid and related derivatives. |
Sterling Winthrop Pharmaceuticals Research Division |
14980663 |
8 |
Novel quinazoline-quinoline alkaloids with cytotoxic and DNA topoisomerase II inhibitory activities. |
Toho University |
15125947 |
38 |
Design, synthesis and structure-activity relationship studies of novel indazole analogues as DNA gyrase inhibitors with Gram-positive antibacterial activity. |
Dainippon Pharmaceutical |
12824037 |
15 |
Synthesis and biological testing of non-fluorinated analogues of levofloxacin. |
Procter & Gamble Pharmaceuticals |
10698436 |
1 |
Preparation of 5-(2,6-dideoxy-2-fluoro-alpha-L-talopyranosyloxy)-6-hydroxynap htho[2,3- f]quinoline-7,12-dione (FT-Alz), a new-type, potentially antitumor substance with various biological activities. |
Institute of Bioorganic Chemistry |
| 46 |
The antitumor activity of novel pyrazoloquinoline derivatives |
TBA |
15026047 |
29 |
Inhibitory activities against topoisomerase I and II by polyhydroxybenzoyl amide derivatives and their structure-activity relationship. |
Kumamoto University |
10743939 |
63 |
Synthesis and biological activities of NB-506 analogues modified at the glucose group. |
Banyu Tsukuba Research Institute |
31416740 |
10 |
Design, Synthesis and Anticancer Evaluation of New Substituted Thiophene-Quinoline Derivatives. |
Kyushu Institute of Technology1-1 Sensuicho |
10340602 |
100 |
Synthesis and biological activities of topoisomerase I inhibitors, 6-N-amino analogues of NB-506. |
Banyu Tsukuba Research Institute |
32084316 |
3 |
Discovery of 4,6- |
Hubei University of Technology |
30846253 |
126 |
Design, synthesis and biological evaluation of 1,4-dihydroxyanthraquinone derivatives as anticancer agents. |
Guangxi University |
15914002 |
9 |
Synthetic lanostane-type triterpenoids as inhibitors of DNA topoisomerase II. |
Osaka University of Pharmaceutical Sciences |
15380226 |
14 |
Synthesis and antibacterial activity of novel 6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-4-oxoquinoline-3-carboxylic acids bearing cyclopropane-fused 2-amino-8-azabicyclo[4.3.0]nonan-8-yl substituents at the C-7 position. |
Daiichi Pharmaceutical |
12459024 |
3 |
Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 1. |
Dainippon Pharmaceutical |
11170652 |
19 |
seco-Cyclothialidines: new concise synthesis, inhibitory activity toward bacterial and human DNA topoisomerases, and antibacterial properties. |
Bayer |
9804687 |
12 |
Synthesis and antitumor activity of new glycosides of epipodophyllotoxin, analogues of etoposide, and NK 611. |
Umr 176 Cnrs/Institut Curie |
9784102 |
13 |
Design of new topoisomerase II inhibitors based upon a quinobenzoxazine self-assembly model. |
The University of Texas At Austin |
9733489 |
24 |
Synthesis and antitumor activity of 4-aminomethylthioxanthenone and 5-aminomethylbenzothiopyranoindazole derivatives. |
Sanofi Winthrop |
9599244 |
4 |
Antitumor agents. 185. Synthesis and biological evaluation of tridemethylthiocolchicine analogues as novel topoisomerase II inhibitors. |
University of North Carolina At Chapel Hill |
7699707 |
7 |
Dicationic diarylfurans as anti-Pneumocystis carinii agents. |
Georgia State University |
7650675 |
25 |
9-substituted acridine derivatives with long half-life and potent antitumor activity: synthesis and structure-activity relationships. |
Sloan-Kettering Institute For Cancer Research |
15177438 |
3 |
6-Arylamino-7-chloro-quinazoline-5,8-diones as novel cytotoxic and DNA topoisomerase inhibitory agents. |
Ewha Womans University |