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27 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
8410993 24 Mammalian topoisomerase II inhibitory activity of 1-cyclopropyl-6,8- difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarb oxylic acid and related derivatives.EBI Sterling Winthrop Pharmaceuticals Research Division
14980663 8 Novel quinazoline-quinoline alkaloids with cytotoxic and DNA topoisomerase II inhibitory activities.EBI Toho University
15125947 38 Design, synthesis and structure-activity relationship studies of novel indazole analogues as DNA gyrase inhibitors with Gram-positive antibacterial activity.EBI Dainippon Pharmaceutical
12824037 15 Synthesis and biological testing of non-fluorinated analogues of levofloxacin.EBI Procter & Gamble Pharmaceuticals
10698436 1 Preparation of 5-(2,6-dideoxy-2-fluoro-alpha-L-talopyranosyloxy)-6-hydroxynap htho[2,3- f]quinoline-7,12-dione (FT-Alz), a new-type, potentially antitumor substance with various biological activities.EBI Institute of Bioorganic Chemistry
 46 The antitumor activity of novel pyrazoloquinoline derivativesEBI TBA
15026047 29 Inhibitory activities against topoisomerase I and II by polyhydroxybenzoyl amide derivatives and their structure-activity relationship.EBI Kumamoto University
10743939 63 Synthesis and biological activities of NB-506 analogues modified at the glucose group.EBI Banyu Tsukuba Research Institute
31416740 10 Design, Synthesis and Anticancer Evaluation of New Substituted Thiophene-Quinoline Derivatives.EBI Kyushu Institute of Technology1-1 Sensuicho
10340602 100 Synthesis and biological activities of topoisomerase I inhibitors, 6-N-amino analogues of NB-506.EBI Banyu Tsukuba Research Institute
32084316 3 Discovery of 4,6-EBI Hubei University of Technology
30846253 126 Design, synthesis and biological evaluation of 1,4-dihydroxyanthraquinone derivatives as anticancer agents.EBI Guangxi University
15914002 9 Synthetic lanostane-type triterpenoids as inhibitors of DNA topoisomerase II.EBI Osaka University of Pharmaceutical Sciences
15380226 14 Synthesis and antibacterial activity of novel 6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-4-oxoquinoline-3-carboxylic acids bearing cyclopropane-fused 2-amino-8-azabicyclo[4.3.0]nonan-8-yl substituents at the C-7 position.EBI Daiichi Pharmaceutical
12459024 3 Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 1.EBI Dainippon Pharmaceutical
11170652 19 seco-Cyclothialidines: new concise synthesis, inhibitory activity toward bacterial and human DNA topoisomerases, and antibacterial properties.EBI Bayer
9804687 12 Synthesis and antitumor activity of new glycosides of epipodophyllotoxin, analogues of etoposide, and NK 611.EBI Umr 176 Cnrs/Institut Curie
9784102 13 Design of new topoisomerase II inhibitors based upon a quinobenzoxazine self-assembly model.EBI The University of Texas At Austin
9733489 24 Synthesis and antitumor activity of 4-aminomethylthioxanthenone and 5-aminomethylbenzothiopyranoindazole derivatives.EBI Sanofi Winthrop
9599244 4 Antitumor agents. 185. Synthesis and biological evaluation of tridemethylthiocolchicine analogues as novel topoisomerase II inhibitors.EBI University of North Carolina At Chapel Hill
7699707 7 Dicationic diarylfurans as anti-Pneumocystis carinii agents.EBI Georgia State University
7650675 25 9-substituted acridine derivatives with long half-life and potent antitumor activity: synthesis and structure-activity relationships.EBI Sloan-Kettering Institute For Cancer Research
15177438 3 6-Arylamino-7-chloro-quinazoline-5,8-diones as novel cytotoxic and DNA topoisomerase inhibitory agents.EBI Ewha Womans University