The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
17125246 |
11 |
Discovery and development of 5-[(5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non-7-yl-methyl]-3-thiophenecarboxylic acid (BMS-587101)--a small molecule antagonist of leukocyte function associated antigen-1. |
Cerep |
24900456 |
46 |
Discovery and Development of Potent LFA-1/ICAM-1 Antagonist SAR 1118 as an Ophthalmic Solution for Treating Dry Eye. |
TBA |
12643901 |
42 |
N-Benzoyl amino acids as LFA-1/ICAM inhibitors 1: amino acid structure-activity relationship. |
Genentech |
15109637 |
30 |
Statin-derived 1,3-oxazinan-2-ones as submicromolar inhibitors of LFA-1/ICAM-1 interaction: stabilization of the metabolically labile vanillyl side chain. |
Novartis Institutes For Biomedical Research |
15080978 |
66 |
N-Benzoyl amino acids as ICAM/LFA-1 inhibitors. Part 2: structure-activity relationship of the benzoyl moiety. |
Genentech |
12565959 |
9 |
1,4-Diazepane-2-ones as novel inhibitors of LFA-1. |
Novartis Institute For Biomedical Research |
11520199 |
25 |
Discovery of potent antagonists of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction. 3. Amide (C-ring) structure-activity relationship and improvement of overall properties of arylthio cinnamides. |
Abbott Laboratories |
11327603 |
31 |
Discovery and SAR of diarylsulfide cyclopropylamide LFA-1/ICAM-1 interaction antagonists. |
Abbott Laboratories |
11052808 |
75 |
Discovery of novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 1. Identification of an additional binding pocket based on an anilino diaryl sulfide lead. |
Abbott Laboratories |
10853677 |
34 |
Discovery and evaluation of potent, tyrosine-based alpha4beta1 integrin antagonists. |
Celltech Chiroscience |
10072689 |
39 |
Selective, tight-binding inhibitors of integrin alpha4beta1 that inhibit allergic airway responses. |
Biogen |
11374943 |
2 |
Antimalarial, cytotoxic, and antifungal alkaloids from Duguetia hadrantha. |
University of Mississippi |
15165136 |
4 |
A new antimalarial quassinoid from Simaba orinocensis. |
University of Mississippi |