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16 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
8691426 114 Synthesis and structure-activity relationships of 2-substituted D-tryptophan-containing peptidic endothelin receptor antagonists: importance of the C-2 substituent of the D-tryptophan residue for endothelin A and B receptor subtype selectivity.EBI Tsukuba Research Institute
1315867 31 Endothelin: a new challenge.EBI Warner-Lambert
9873432 52 Endothelin antagonists: discovery of EMD 122946, a highly potent and orally active ETA selective antagonist.EBI Merck
 30 IRL 2500: A potent ETB selective endothelin antagonistEBI TBA
 20 Synthesis of 2-substituted d-tryptophan-containing peptide derivatives with endothelin receptor antagonist activityEBI TBA
 56 Pyridazinones with a pendant acylsulfonamide moiety as endothelin receptor antagonistsEBI TBA
11985472 185 Structure-activity relationships of a novel class of endothelin-A receptor antagonists and discovery of potent and selective receptor antagonist, 2-(benzo[1,3]dioxol-5-yl)-6-isopropyloxy-4-(4-methoxyphenyl)-2H-chromene-3-carboxylic acid (S-1255). 1. Study on structure-activity relationships and basEBI Shionogi
11229770 28 Peptoids as endothelin receptor antagonists.EBI Ranbaxy Laboratories
10969989 45 Discovery and synthesis of a potent sulfonamide ET(B) selective antagonist.EBI Shionogi
27321813 286 From bosentan (TracleerŪ) to macitentan (OpsumitŪ): The medicinal chemistry perspective.EBI Actelion Pharmaceuticals
9379441 100 Pyrrolidine-3-carboxylic acids as endothelin antagonists. 2. Sulfonamide-based ETA/ETB mixed antagonists.EBI Abbott Laboratories
9022798 58 Potent and selective non-benzodioxole-containing endothelin-A receptor antagonists.EBI Abbott Laboratories
8676339 143 2,4-Diarylpyrrolidine-3-carboxylic acids--potent ETA selective endothelin receptor antagonists. 1. Discovery of A-127722.EBI Abbott Laboratories
8632420 112 Azole endothelin antagonists. 2. Structure-activity studies.EBI Abbott Laboratories
8632419 50 Azole endothelin antagonists. 1. A receptor model explains an unusual structure-activity profile.EBI Abbott Laboratories
7473559 85 Structure-activity relationships of cyclic pentapeptide endothelin A receptor antagonists.EBI Tsukuba Research Institute