The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
22468936 |
49 |
Discovery of a novel alpha-7 nicotinic acetylcholine receptor agonist series and characterization of the potent, selective, and orally efficacious agonist 5-(4-acetyl[1,4]diazepan-1-yl)pentanoic acid [5-(4-methoxyphenyl)-1H-pyrazol-3-yl] amide (SEN15924, WAY-361789). |
Siena Biotech |
20591663 |
23 |
Identification of novel alpha7 nAChR positive allosteric modulators with the use of pharmacophore in silico screening methods. |
Glaxosmithkline |
19026537 |
90 |
3D-QSAR and QSSR studies of 3,8-diazabicyclo[4.2.0]octane derivatives as neuronal nicotinic acetylcholine receptors by comparative molecular field analysis (CoMFA). |
Burnham Institute For Medical Research |
23083093 |
25 |
N-[5-(5-fluoropyridin-3-yl)-1H-pyrazol-3-yl]-4-piperidin-1-ylbutyramide (SEN78702, WYE-308775): a medicinal chemistry effort toward ana7 nicotinic acetylcholine receptor agonist preclinical candidate. |
Siena Biotech |
19576766 |
86 |
Synthesis and SAR studies of 1,4-diazabicyclo[3.2.2]nonane phenyl carbamates--subtype selective, high affinity alpha7 nicotinic acetylcholine receptor agonists. |
Pfizer |
18989912 |
95 |
Novel acetylcholine and carbamoylcholine analogues: development of a functionally selective alpha4beta2 nicotinic acetylcholine receptor agonist. |
University of Copenhagen |
9484491 |
23 |
Identification and initial structure-activity relationships of (R)-5-(2-azetidinylmethoxy)-2-chloropyridine (ABT-594), a potent, orally active, non-opiate analgesic agent acting via neuronal nicotinic acetylcholine receptors. |
Abbott Laboratories |
11212100 |
27 |
The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist. |
Astrazeneca |
19232492 |
32 |
Preparation and characterization of N-(3-pyridinyl) spirocyclic diamines as ligands for nicotinic acetylcholine receptors. |
Abbott Laboratories |
19027295 |
108 |
Carbamoylcholine analogs as nicotinic acetylcholine receptor agonists--structural modifications of 3-(dimethylamino)butyl dimethylcarbamate (DMABC). |
Copenhagen University |
18789861 |
26 |
Discovery and optimization of substituted piperidines as potent, selective, CNS-penetrant alpha4beta2 nicotinic acetylcholine receptor potentiators. |
Amgen |
11312774 |
36 |
Neonicotinoid insecticides: molecular features conferring selectivity for insect versus mammalian nicotinic receptors. |
University of California |
25626527 |
6 |
Novel Diketopiperazine Dihydroorotate Dehydrogenase Inhibitors Purified from Traditional Tibetan Animal Medicine Osteon Myospalacem Baileyi. |
Chinese Academy of Sciences |
26469307 |
7 |
Phosphorylation of Capsaicinoid Derivatives Provides Highly Potent and Selective Inhibitors of the Transcription Factor STAT5b. |
University of Leipzig |