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16 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
32324396 17 p62/SQSTM1, a Central but Unexploited Target: Advances in Its Physiological/Pathogenic Functions and Small Molecular Modulators.EBI China Pharmaceutical University
32832028 47 Stereochemical Differences in Fluorocyclopropyl Amides Enable Tuning of Btk Inhibition and Off-Target Activity.EBI Genentech
32832022 33 Discovery of Potent and Orally Available Bicyclo[1.1.1]pentane-Derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors.EBI Merck
32551006 134 Discovery of an Atropisomeric PI3K? Selective Inhibitor through Optimization of the Hinge Binding Motif.EBI Gilead Sciences
32035698 40 Discovery and SAR of aryl hydroxy pyrimidinones as potent small molecule agonists of the GPCR APJ.EBI Bristol-Myers Squibb Research and Development
27366941 44 Discovery of Novel Thiophene-Based, Thumb Pocket 2 Allosteric Inhibitors of the Hepatitis C NS5B Polymerase with Improved Potency and Physicochemical Profiles.EBI Vertex Pharmaceuticals
31749906 52 Discovery of Amino-cyclobutarene-derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors for Cancer Immunotherapy.EBI Merck
31246024 106 Discovery of Potent Protease-Activated Receptor 4 Antagonists with in Vivo Antithrombotic Efficacy.EBI Bristol-Myers Squibb Research & Development
32297743 59 Discovery of (2EBI Astrazeneca
31851518 61 The Discovery of 7-Methyl-2-[(7-methyl[1,2,4]triazolo[1,5-EBI Astrazeneca
30500190 36 Design and Optimization of Sulfone Pyrrolidine Sulfonamide Antagonists of Transient Receptor Potential Vanilloid-4 with in Vivo Activity in a Pulmonary Edema Model.EBI TBA
30929436 88 Novel Chemical Series of 5-Lipoxygenase-Activating Protein Inhibitors for Treatment of Coronary Artery Disease.EBI TBA
32184970 55 Discovery of Potent and Selective MTH1 Inhibitors for Oncology: Enabling Rapid Target (In)Validation.EBI Gilead Sciences
30638874 64 Discovery of new indole-based acylsulfonamide NaEBI Bristol-Myers Squibb Research and Development