The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 26037610 |
37 |
Discovery and structural analyses of S-adenosyl-L-homocysteine hydrolase inhibitors based on non-adenosine analogs. |
Mitsubishi Tanabe Pharma |
| 26010585 |
13 |
Structure-Activity Relationships of Neplanocin A Analogues as S-Adenosylhomocysteine Hydrolase Inhibitors and Their Antiviral and Antitumor Activities. |
Seoul National University |
| 25022879 |
33 |
Discovery of S-adenosyl-L-homocysteine hydrolase inhibitors based on non-adenosine analogs. |
Mitsubishi Tanabe Pharma |
| 24813734 |
44 |
Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase. |
Merck Research Laboratories |
| 3346868 |
3 |
9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl) derivatives of adenine and 3-deazaadenine: potent inhibitors of bovine liver S-adenosylhomocysteine hydrolase. |
University of Kansas |
| 6283083 |
2 |
1-beta-D-arabinofuranosyl-1H-imidazo[4,5-c]pyridine (ara-3-deazaadenine). |
TBA |
| 18374570 |
8 |
Synthesis of 4'-modified noraristeromycins to clarify the effect of the 4'-hydroxyl groups for inhibitory activity against S-adenosyl-L-homocysteine hydrolase. |
Gifu University |
| 18295495 |
12 |
Synthesis of 2-modified aristeromycins and their analogs as potent inhibitors against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase. |
Gifu University |
| 15887973 |
1 |
Are L-adenosine and its derivatives substrates for S-adenosyl-L-homocysteine hydrolase? |
Florida International University |
| 15456269 |
2 |
Stereoselective synthesis of sugar-modified enyne analogues of adenosine and uridine. Interaction with S-adenosyl-L-homocysteine hydrolase and antiviral and cytotoxic effects. |
Florida International University |
| 15501044 |
5 |
Inactivation of human S-adenosylhomocysteine hydrolase by covalent labeling of cysteine 195 with thionucleoside derivatives. |
Umr 6519 |
| 15501043 |
4 |
Inactivation of S-adenosylhomocysteine hydrolase with haloethyl and dihalocyclopropyl esters derived from homoadenosine-6'-carboxylic acid. |
Umr 6519 |
| 12036374 |
2 |
Sugar-modified conjugated diene analogues of adenosine and uridine: synthesis, interaction with S-adenosyl-L-homocysteine hydrolase, and antiviral and cytostatic effects. |
Florida International University |
| 11495586 |
3 |
Synthesis, mechanism of action, and antiviral activity of a new series of covalent mechanism-based inhibitors of S-adenosyl-L-homocysteine hydrolase. |
Universit£ |
| 9748360 |
3 |
Inactivation of S-adenosyl-L-homocysteine hydrolase and antiviral activity with 5',5',6',6'-tetradehydro-6'-deoxy-6'-halohomoadenosine analogues (4'-haloacetylene analogues derived from adenosine). |
Brigham Young University |
| 9685247 |
3 |
Discovery of type II (covalent) inactivation of S-adenosyl-L-homocysteine hydrolase involving its"hydrolytic activity": synthesis and evaluation of dihalohomovinyl nucleoside analogues derived from adenosine. |
Brigham Young University |
| 9171871 |
7 |
Anticancer and antiviral effects and inactivation of S-adenosyl-L-homocysteine hydrolase with 5'-carboxaldehydes and oximes synthesized from adenosine and sugar-modified analogues. |
Brigham Young University |
| 8863793 |
14 |
Inactivation of S-adenosyl-L-homocysteine hydrolase by amide and ester derivatives of adenosine-5'-carboxylic acid. |
Brigham Young University |
| 7932585 |
5 |
Nucleic acid related compounds. 84. Synthesis of 6'-(E and Z)-halohomovinyl derivatives of adenosine, inactivation of S-adenosyl-L-homocysteine hydrolase, and correlation of anticancer and antiviral potencies with enzyme inhibition. |
Brigham Young University |
| 8464042 |
4 |
Adenosine-5'-carboxaldehyde: a potent inhibitor of S-adenosyl-L-homocysteine hydrolase. |
University of Kansas |
| 1995889 |
14 |
4',5'-unsaturated 5'-halogenated nucleosides. Mechanism-based and competitive inhibitors of S-adenosyl-L-homocysteine hydrolase. |
Merrell Dow Research Institute |
| 2842505 |
5 |
Synthesis and antiviral evaluation of 6'-substituted aristeromycins: potential mechanism-based inhibitors of S-adenosylhomocysteine hydrolase. |
Syntex Research |
| 3411600 |
26 |
Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 11. Molecular dissections of neplanocin A as potential inhibitors of S-adenosylhomocysteine hydrolase. |
University of Kansas |
| 3981539 |
3 |
Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 9. 2',3'-Dialdehyde derivatives of carbocyclic purine nucleosides as inhibitors of S-adenosylhomocysteine hydrolase. |
TBA |
| 12781179 |
4 |
Unexpected inhibition of S-adenosyl-L-homocysteine hydrolase by a guanosine nucleoside. |
Georgia Institute of Technology |
| 12729633 |
3 |
Inactivation of S-adenosyl-L-homocysteine hydrolase with novel 5'-thioadenosine derivatives. Antiviral effects. |
Umr 6519 |
| 11814819 |
3 |
Synthesis of an alpha-aminophosphonate nucleoside as an inhibitor of S-adenosyl-L-homocysteine hydrolase. |
University of Waterloo |
| | 1 |
Synthesis of 4-fluoroadenosine as an inhibitor of S-adenosyl-L-homocysteine hydrolase |
TBA |
| | 5 |
()-7-deazaaristeromycin lacking the hydroxymethyl substituent |
TBA |
| 21226494 |
10 |
X-ray crystal structure and binding mode analysis of human S-adenosylhomocysteine hydrolase complexed with novel mechanism-based inhibitors, haloneplanocin A analogues. |
Ewha Womans University |
| 19692248 |
5 |
A new structural class of S-adenosylhomocysteine hydrolase inhibitors. |
Boston College |
| | 3 |
Adenosine dialdehyde analogs I: Regioselective synthesis of adenosine monoaldehydes |
TBA |
| | 2 |
(E) and (Z)5′-fluoro olefin carbocyclic nucleosides: effect of olefin geometry on inhibition of s-adenosyl-l-homocysteine hydrolase |
TBA |
| | 4 |
Synthesis and evaluation of 4′-5′-dehydro-5′-fluoroaristeromycins as S-adenosyl-L-homocysteine (AdoHcy) hydrolase inhibitors |
TBA |
| 18515116 |
3 |
Synthesis of 3',4'-epoxynoraristeromycin analogs for molecular labeling probe of S-adenosyl-l-homocysteine hydrolase. |
Gifu University |
| 17582766 |
3 |
Design, synthesis, and molecular modeling studies of 5'-deoxy-5'-ureidoadenosine: 5'-ureido group as multiple hydrogen bonding donor in the active site of S-adenosylhomocysteine hydrolase. |
Ewha Womans University |
| 16480257 |
1 |
Inactivation of S-adenosyl-L-homocysteine hydrolase by 6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine and 6'-chloro-6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine. Antiviral and cytotoxic effects. |
TBA |
| 15482939 |
5 |
Synthesis of 5'-substituted fluoro-neplanocin A analogues: importance of a hydrogen bonding donor at 5'-position for the inhibitory activity of S-adenosylhomocysteine hydrolase. |
Pusan National University |
| 15080985 |
4 |
Synthesis of fluorinated cyclopentenyladenine as potent inhibitor of S-adenosylhomocysteine hydrolase. |
Ewha Womans University |
| 14592485 |
8 |
Synthesis of 2-fluoronoraristeromycin and its inhibitory activity against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase. |
Gifu University |
| 32182061 |
5 |
Metabolic and Pharmaceutical Aspects of Fluorinated Compounds. |
Bristol Myers Squibb |
| 31841728 |
7 |
Identification of 6'-?-fluoro-homoaristeromycin as a potent inhibitor of chikungunya virus replication. |
Seoul National University |
| 10509926 |
1 |
9-[(2'S,3'S)-3'-formyl-2',3'-dihydroxypropyl]adenine: a facile affinity-labeling probe of human S-adenosyl-L-homocysteine hydrolase. |
Gifu University |
| 30883119 |
14 |
Discovery of Bisubstrate Inhibitors for Protein N-Terminal Methyltransferase 1. |
Purdue University |
| 31244113 |
27 |
Design, Synthesis, and Anti-RNA Virus Activity of 6'-Fluorinated-Aristeromycin Analogues. |
Seoul National University |
| 31724854 |
30 |
Novel Propargyl-Linked Bisubstrate Analogues as Tight-Binding Inhibitors for Nicotinamide |
TBA |
| 9046353 |
2 |
(+)-7-Deaza-5'-noraristeromycin as an anti-trypanosomal agent. |
Auburn University |
| 8691429 |
4 |
Aristeromycin-5'-carboxaldehyde: a potent inhibitor of S-adenosyl-L-homocysteine hydrolase. |
University of Kansas |
| 8120872 |
2 |
Antiviral enantiomeric preference for 5'-noraristeromycin. |
University of South Florida |
| 8691433 |
2 |
New neplanocin analogues. 6. Synthesis and potent antiviral activity of 6'-homoneplanocin A1. |
Hokkaido University |
| 30385162 |
1 |
6'-Fluoro-3-deazaneplanocin: Synthesis and antiviral properties, including Ebola. |
Auburn University |
| 2738875 |
1 |
Oxidation of neplanocin A to the corresponding 3'-keto derivative by S-adenosylhomocysteine hydrolase. |
University of Kansas |
| 1732550 |
12 |
New neplanocin analogues. 1. Synthesis of 6'-modified neplanocin A derivatives as broad-spectrum antiviral agents. |
Toyo Jozo |
| 1588558 |
9 |
4'-modified analogues of aristeromycin and neplanocin A: synthesis and inhibitory activity toward S-adenosyl-L-homocysteine hydrolase. |
University of Kansas |
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