37 articles for thisTarget

---

The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
27682507	167	Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300.	Genentech
27326325	44	GSK6853, a Chemical Probe for Inhibition of the BRPF1 Bromodomain.	Glaxosmithkline
27167503	17	Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.	University of Z£Rich
26982797	20	The"Gatekeeper" Residue Influences the Mode of Binding of Acetyl Indoles to Bromodomains.	University of Z£Rich
26731611	30	4-Acyl Pyrrole Derivatives Yield Novel Vectors for Designing Inhibitors of the Acetyl-Lysine Recognition Site of BRD4(1).	Albert-Ludwigs-University of Freiburg
26572217	60	Disrupting Acetyl-Lysine Recognition: Progress in the Development of Bromodomain Inhibitors.	Genentech
26061247	71	Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.	The University of Texas M.D. Anderson Cancer Center
25974391	78	Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.	University of Oxford
26230603	176	Structure-Based Optimization of Naphthyridones into Potent ATAD2 Bromodomain Inhibitors.	Glaxosmithkline
25408830	43	1,3-Dimethyl Benzimidazolones Are Potent, Selective Inhibitors of the BRPF1 Bromodomain.	Glaxosmithkline
25249180	146	The discovery of I-BET726 (GSK1324726A), a potent tetrahydroquinoline ApoA1 up-regulator and selective BET bromodomain inhibitor.	Glaxosmithkline
25856009	5	Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition.	Glaxosmithkline R&D
27757418	27	Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia.	University of Oxford
29170712	4	Chemical probes and inhibitors of bromodomains outside the BET family.	University of Oxford
32410449	88	Application of Atypical Acetyl-lysine Methyl Mimetics in the Development of Selective Inhibitors of the Bromodomain-Containing Protein 7 (BRD7)/Bromodomain-Containing Protein 9 (BRD9) Bromodomains.	Glaxosmithkline R&D
32453591	70	Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib.	University of Illinois At Chicago
27219867	94	Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains.	Genentech
31789032	106	Discovery of Benzo[	China Pharmaceutical University
30606676	83	Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitor.	Gilead Sciences
31398032	113	A Qualified Success: Discovery of a New Series of ATAD2 Bromodomain Inhibitors with a Novel Binding Mode Using High-Throughput Screening and Hit Qualification.	Cellzome
29902720	80	Structure-based discovery of selective BRPF1 bromodomain inhibitors.	University of Zurich
29656650	151	Discovery of Tetrahydroquinoxalines as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the Second Bromodomain.	University of Strathclyde
29169673	115	Design and synthesis of a biaryl series as inhibitors for the bromodomains of CBP/P300.	Wuxi Apptec
28463487	185	Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor.	University of Michigan
30015487	96	Structure-Based Discovery of CF53 as a Potent and Orally Bioavailable Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitor.	TBA
28892380	93	GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP).	Genentech
28068087	80	Design of a Biased Potent Small Molecule Inhibitor of the Bromodomain and PHD Finger-Containing (BRPF) Proteins Suitable for Cellular and in Vivo Studies.	University College London
28402630	4	Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains.	Bayer
28714688	4	Design of a Chemical Probe for the Bromodomain and Plant Homeodomain Finger-Containing (BRPF) Family of Proteins.	University College London
28949521	88	Discovery of N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/Mivebresib), a Potent and Orally Available Bromodomain and Extraterminal Domain (BET) Family Bromodomain Inhibitor.	Abbvie
28849908	13	Selective Targeting of Bromodomains of the Bromodomain-PHD Fingers Family Impairs Osteoclast Differentiation.	Oxford University