null
SMILES: NCC(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
InChI Key: InChIKey=AMWPZASLDLLQFT-JJNLEZRASA-N
PDB links: 9 PDB IDs match this monomer. 25 PDB IDs contain this monomer as substructures. 25 PDB IDs contain inhibitors having a similarity of 90% to this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycine--tRNA ligase (Bombyx mori) | BDBM18138 (2-amino-1-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 50 | -9.95 | 2.00E+3 | 270 | n/a | n/a | n/a | 7.5 | 25 |
Medical College of Ohio | Assay Description Aminoacyl-tRNA synthetase assays were measuring the incorporation of [14C] amino acid into tRNA. | Biochemistry 42: 5333-40 (2003) Article DOI: 10.1021/bi030031h BindingDB Entry DOI: 10.7270/Q2HQ3X6H | |||||||||||
More data for this Ligand-Target Pair |
Cell (A) | Syringe (B) | Cell Links | Syringe Links | Cell + Syr Links | ΔG° kcal/mole | -TΔS° kcal/mole | ΔH° kcal/mole | log K | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|
tRNA synthetase (GlyRS) (Bombyx mori) | BDBM18138 (2-amino-1-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-...) | GoogleScholar | MMDB PC cid PC sid PDB | -8.93 | 35.6 | -44.7 | 6.57 | 7.20 | 24.9 | |
Medical College of Ohio | Biochemistry 42: 5333-40 (2003) |