BDBM50041959 ((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::(+)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::(1S,2R)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::AJ76(+)::CHEMBL27441

SMILES: CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C

InChI Key: InChIKey=YGHLYBIUVOLKCV-SMDDNHRTSA-N

Data: 18 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50041959   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description Compound was tested for agonistic activity against D2 receptor from cloned CHO cells, used [3H]U-86170 as radioligand				J Med Chem 36: 1301-15 (1993) BindingDB Entry DOI: 10.7270/Q2TD9Z06
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity of the compound was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone)				Bioorg Med Chem Lett 4: 689-694 (1994) Article DOI: 10.1016/S0960-894X(01)80181-5 BindingDB Entry DOI: 10.7270/Q2SX6D5J
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Göteborg Curated by ChEMBL					Assay Description Binding towards Dopamine receptor D3 expressed in CHO-K1 cells using [3H]spiperone				J Med Chem 36: 3188-96 (1993) BindingDB Entry DOI: 10.7270/Q2VH5MWJ
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cells				J Med Chem 46: 4377-92 (2003) Article DOI: 10.1021/jm030085p BindingDB Entry DOI: 10.7270/Q21V5FPS
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
U. 109 Curated by PDSP Ki Database									Nature 347: 146-51 (1990) Article DOI: 10.1038/347146a0 BindingDB Entry DOI: 10.7270/Q2CC0Z5N
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity of the compound was measured at cloned mammalian dopamine D4 receptor expressed in CHO-K1 cells (using [3H]- spiperone)				Bioorg Med Chem Lett 4: 689-694 (1994) Article DOI: 10.1016/S0960-894X(01)80181-5 BindingDB Entry DOI: 10.7270/Q2SX6D5J
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Göteborg Curated by ChEMBL					Assay Description Binding towards dopamine receptor D4 expressed in CHO-K1 cells using [3H]spiperone				J Med Chem 36: 3188-96 (1993) BindingDB Entry DOI: 10.7270/Q2VH5MWJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Maryland Psychiatric Research Center Curated by PDSP Ki Database									Eur J Pharmacol 236: 483-6 (1993) Article DOI: 10.1016/0014-2999(93)90488-4 BindingDB Entry DOI: 10.7270/Q25Q4TKG
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	132	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Maryland Psychiatric Research Center Curated by PDSP Ki Database									Eur J Pharmacol 236: 483-6 (1993) Article DOI: 10.1016/0014-2999(93)90488-4 BindingDB Entry DOI: 10.7270/Q25Q4TKG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity of the compound was measured at cloned mammalian dopamine D2 receptor expressed in CHO-K1 cells (using [3H]-U-86,170)				Bioorg Med Chem Lett 4: 689-694 (1994) Article DOI: 10.1016/S0960-894X(01)80181-5 BindingDB Entry DOI: 10.7270/Q2SX6D5J
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Göteborg Curated by ChEMBL					Assay Description Binding towards Dopamine receptor D2 expressed in CHO-K1 cells using [3H]-U-86,170				J Med Chem 36: 3188-96 (1993) BindingDB Entry DOI: 10.7270/Q2VH5MWJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Göteborg Curated by ChEMBL					Assay Description Binding towards Dopamine receptor D2 expressed in CHO-K1 cells using [3H]-U-86,170				J Med Chem 36: 3188-96 (1993) BindingDB Entry DOI: 10.7270/Q2VH5MWJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	179	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligand				J Med Chem 36: 1301-15 (1993) BindingDB Entry DOI: 10.7270/Q2TD9Z06
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Göteborg Curated by ChEMBL					Assay Description Binding towards Dopamine receptor D2 expressed in CHO-K1 cells using [3H]-U-86,170				J Med Chem 36: 3188-96 (1993) BindingDB Entry DOI: 10.7270/Q2VH5MWJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor from bovine hippocampus, used [3H]8-OH-DPAT as radioligand				J Med Chem 36: 1301-15 (1993) BindingDB Entry DOI: 10.7270/Q2TD9Z06
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	438	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by PDSP Ki Database									J Pharmacol Exp Ther 264: 1002-11 (1993) BindingDB Entry DOI: 10.7270/Q2T1525C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Göteborg Curated by ChEMBL					Assay Description Binding towards Dopamine receptor D2 using [3H]-spiperone from rat striatal membrane				J Med Chem 36: 3188-96 (1993) BindingDB Entry DOI: 10.7270/Q2VH5MWJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 5A (Homo sapiens (Human))	BDBM50041959 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	2.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity of the compound was measured at cloned mammalian 5-HT1A receptor expressed in CHO-K1 cells (using [3H]-8-OH-DPAT )				Bioorg Med Chem Lett 4: 689-694 (1994) Article DOI: 10.1016/S0960-894X(01)80181-5 BindingDB Entry DOI: 10.7270/Q2SX6D5J
					More data for this Ligand-Target Pair