BDBM85213 Agmatine::CAS_306-60-5::CHEMBL58343::NSC_199::US8633208, Agmatine
SMILES: [#7]-[#6]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7]
InChI Key: InChIKey=QYPPJABKJHAVHS-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Polyamine oxidase 1 (Zea mays) | BDBM85213 (Agmatine | CAS_306-60-5 | CHEMBL58343 | NSC_199 | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 6.5 | n/a |
Universit£ degli Studi di Siena Curated by ChEMBL | Assay Description Inhibition of maize PAO at pH 6.5 by spectrophotometry-based Dixon plot method | J Med Chem 52: 4774-85 (2009) Article DOI: 10.1021/jm900371z BindingDB Entry DOI: 10.7270/Q2TB16W1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nischarin (RAT) | BDBM85213 (Agmatine | CAS_306-60-5 | CHEMBL58343 | NSC_199 | ...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by PDSP Ki Database | J Pharmacol Exp Ther 285: 170-7 (1998) BindingDB Entry DOI: 10.7270/Q27H1H4B | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ionotropic glutamate receptor subunit Delta2 (Xenopus) | BDBM85213 (Agmatine | CAS_306-60-5 | CHEMBL58343 | NSC_199 | ...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Curated by PDSP Ki Database | J Pharmacol Exp Ther 305: 740-8 (2003) Article DOI: 10.1124/jpet.102.045799 BindingDB Entry DOI: 10.7270/Q2N878C5 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nischarin (RAT) | BDBM85213 (Agmatine | CAS_306-60-5 | CHEMBL58343 | NSC_199 | ...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by PDSP Ki Database | J Pharmacol Exp Ther 285: 170-7 (1998) BindingDB Entry DOI: 10.7270/Q27H1H4B | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 1 (RAT) | BDBM85213 (Agmatine | CAS_306-60-5 | CHEMBL58343 | NSC_199 | ...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 8.60E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cologne Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of uptake of 0.1 uM MPP+ in OCT1-expressing 293 cells | J Pharmacol Exp Ther 304: 810-7 (2003) Article DOI: 10.1124/jpet.102.044404 BindingDB Entry DOI: 10.7270/Q2QC04RF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 1 (Homo sapiens (Human)) | BDBM85213 (Agmatine | CAS_306-60-5 | CHEMBL58343 | NSC_199 | ...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 2.40E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cologne Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of uptake of 0.1 uM MPP+ in OCT1-expressing 293 cells | J Pharmacol Exp Ther 304: 810-7 (2003) Article DOI: 10.1124/jpet.102.044404 BindingDB Entry DOI: 10.7270/Q2QC04RF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nischarin (RAT) | BDBM85213 (Agmatine | CAS_306-60-5 | CHEMBL58343 | NSC_199 | ...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Gdansk University of Technology Curated by ChEMBL | Assay Description Inhibition of Wistar rat imidazoline I1 receptor | Bioorg Med Chem 19: 156-67 (2011) Article DOI: 10.1016/j.bmc.2010.11.039 BindingDB Entry DOI: 10.7270/Q2GH9J79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nischarin (RAT) | BDBM85213 (Agmatine | CAS_306-60-5 | CHEMBL58343 | NSC_199 | ...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Gda£?sk University of Technology Curated by ChEMBL | Assay Description Displacement of [3H]clonidine from imidazoline I1 receptor in Wistar rat kidney by liquid scintillation counting | Bioorg Med Chem Lett 19: 1009-11 (2009) Article DOI: 10.1016/j.bmcl.2008.11.055 BindingDB Entry DOI: 10.7270/Q2125SJ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM85213 (Agmatine | CAS_306-60-5 | CHEMBL58343 | NSC_199 | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Rottapharm S.p.A US Patent | Assay Description Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti... | US Patent US8633208 (2014) BindingDB Entry DOI: 10.7270/Q23J3BMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM85213 (Agmatine | CAS_306-60-5 | CHEMBL58343 | NSC_199 | ...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Rottapharm S.p.A US Patent | Assay Description Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti... | US Patent US8633208 (2014) BindingDB Entry DOI: 10.7270/Q23J3BMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Deoxyhypusine synthase (Rattus norvegicus) | BDBM85213 (Agmatine | CAS_306-60-5 | CHEMBL58343 | NSC_199 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.56E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Dental Research Curated by ChEMBL | Assay Description In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase. | J Med Chem 38: 3053-61 (1995) BindingDB Entry DOI: 10.7270/Q2P55MJ2 | |||||||||||
More data for this Ligand-Target Pair |