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SMILES: Cn1nnc(n1)-c1c(F)cc(Cl)cc1-c1ccc2C(CCOc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F

InChI Key: InChIKey=ULEVRJKNZJLMMK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107166   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kininogen-1 (Homo sapiens (Human))	BDBM107166 (US8592426, 15) Show SMILES Cn1nnc(n1)-c1c(F)cc(Cl)cc1-c1ccc2C(CCOc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F Show InChI InChI=1S/C23H19ClF4N6O3/c1-34-32-19(31-33-34)18-14(9-12(24)10-15(18)25)11-2-3-13-16(4-7-37-17(13)8-11)29-20(35)22(5-6-22)30-21(36)23(26,27)28/h2-3,8-10,16H,4-7H2,1H3,(H,29,35)(H,30,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Binding assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair
Kininogen-1 (Homo sapiens (Human))	BDBM107166 (US8592426, 15) Show SMILES Cn1nnc(n1)-c1c(F)cc(Cl)cc1-c1ccc2C(CCOc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F Show InChI InChI=1S/C23H19ClF4N6O3/c1-34-32-19(31-33-34)18-14(9-12(24)10-15(18)25)11-2-3-13-16(4-7-37-17(13)8-11)29-20(35)22(5-6-22)30-21(36)23(26,27)28/h2-3,8-10,16H,4-7H2,1H3,(H,29,35)(H,30,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24.6	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Calcium mobilization assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair