Found 7 hits for monomerid = 11056 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM11056
![PNG](/data/jpeg/tenK1/BindingDB_11056.png) ((2S)-1-[(2S)-pyrrolidin-2-ylcarbonyl]pyrrolidine-2...)Show InChI InChI=1S/C10H15N3O/c11-7-8-3-2-6-13(8)10(14)9-4-1-5-12-9/h8-9,12H,1-6H2/t8-,9-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 20 | -10.4 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories
| Assay Description The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea... |
J Med Chem 49: 3520-35 (2006)
Article DOI: 10.1021/jm051283e BindingDB Entry DOI: 10.7270/Q2WS8RG1 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM11056
![PNG](/data/jpeg/tenK1/BindingDB_11056.png) ((2S)-1-[(2S)-pyrrolidin-2-ylcarbonyl]pyrrolidine-2...)Show InChI InChI=1S/C10H15N3O/c11-7-8-3-2-6-13(8)10(14)9-4-1-5-12-9/h8-9,12H,1-6H2/t8-,9-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In vitro test for inhibitory activity against human dipeptidyl peptidase IV. |
Bioorg Med Chem Lett 6: 1163-1166 (1996)
Article DOI: 10.1016/0960-894X(96)00190-4 BindingDB Entry DOI: 10.7270/Q279455Q |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM11056
![PNG](/data/jpeg/tenK1/BindingDB_11056.png) ((2S)-1-[(2S)-pyrrolidin-2-ylcarbonyl]pyrrolidine-2...)Show InChI InChI=1S/C10H15N3O/c11-7-8-3-2-6-13(8)10(14)9-4-1-5-12-9/h8-9,12H,1-6H2/t8-,9-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation
Curated by ChEMBL
| Assay Description Inhibition of DPP4 in human plasma by fluorescence assay |
Bioorg Med Chem 15: 641-55 (2006)
Article DOI: 10.1016/j.bmc.2006.10.059 BindingDB Entry DOI: 10.7270/Q21N81X1 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM11056
![PNG](/data/jpeg/tenK1/BindingDB_11056.png) ((2S)-1-[(2S)-pyrrolidin-2-ylcarbonyl]pyrrolidine-2...)Show InChI InChI=1S/C10H15N3O/c11-7-8-3-2-6-13(8)10(14)9-4-1-5-12-9/h8-9,12H,1-6H2/t8-,9-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human DPP4 |
Bioorg Med Chem 15: 2631-50 (2007)
Article DOI: 10.1016/j.bmc.2007.01.041 BindingDB Entry DOI: 10.7270/Q2CV4HDR |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM11056
![PNG](/data/jpeg/tenK1/BindingDB_11056.png) ((2S)-1-[(2S)-pyrrolidin-2-ylcarbonyl]pyrrolidine-2...)Show InChI InChI=1S/C10H15N3O/c11-7-8-3-2-6-13(8)10(14)9-4-1-5-12-9/h8-9,12H,1-6H2/t8-,9-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation
Curated by ChEMBL
| Assay Description Inhibitory concentration against human dipeptidyl-peptidase IV |
Bioorg Med Chem Lett 15: 2441-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.03.077 BindingDB Entry DOI: 10.7270/Q27P8XWJ |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase IV
(Rattus norvegicus (rat)) | BDBM11056
![PNG](/data/jpeg/tenK1/BindingDB_11056.png) ((2S)-1-[(2S)-pyrrolidin-2-ylcarbonyl]pyrrolidine-2...)Show InChI InChI=1S/C10H15N3O/c11-7-8-3-2-6-13(8)10(14)9-4-1-5-12-9/h8-9,12H,1-6H2/t8-,9-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation
Curated by ChEMBL
| Assay Description Inhibitory concentration against rat dipeptidyl-peptidase IV |
Bioorg Med Chem Lett 15: 2441-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.03.077 BindingDB Entry DOI: 10.7270/Q27P8XWJ |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM11056
![PNG](/data/jpeg/tenK1/BindingDB_11056.png) ((2S)-1-[(2S)-pyrrolidin-2-ylcarbonyl]pyrrolidine-2...)Show InChI InChI=1S/C10H15N3O/c11-7-8-3-2-6-13(8)10(14)9-4-1-5-12-9/h8-9,12H,1-6H2/t8-,9-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human DPP4 |
Bioorg Med Chem 15: 2715-35 (2007)
Article DOI: 10.1016/j.bmc.2007.01.033 BindingDB Entry DOI: 10.7270/Q2NC60W7 |
More data for this Ligand-Target Pair | |