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SMILES: CS(=O)(=O)c1cc(ccc1C#N)-c1ccc(C[C@H](NC(=O)[C@]23CC[C@@H](CN2)C3)C#N)cc1

InChI Key: InChIKey=PZLHFILSWHGRPR-QATBIIFWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139516   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 1


(Homo sapiens (Human))		BDBM139516
PNG
(US8889708, 14)
Show SMILES CS(=O)(=O)c1cc(ccc1C#N)-c1ccc(C[C@H](NC(=O)[C@]23CC[C@@H](CN2)C3)C#N)cc1 |r|
Show InChI InChI=1S/C24H24N4O3S/c1-32(30,31)22-11-19(6-7-20(22)13-25)18-4-2-16(3-5-18)10-21(14-26)28-23(29)24-9-8-17(12-24)15-27-24/h2-7,11,17,21,27H,8-10,12,15H2,1H3,(H,28,29)/t17-,21+,24-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
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PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 650n/an/an/an/an/a25



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys...

US Patent US8889708 (2014)


BindingDB Entry DOI: 10.7270/Q2JM28BB
More data for this
Ligand-Target Pair