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SMILES: Fc1cc(ccc1C[C@H](NC(=O)C12CCC(CC1)CN2)C#N)-c1cnn(CC2CCOCC2)c1

InChI Key: InChIKey=FIBMSYAXRBDRDO-DTWLZNLASA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139530   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 1


(Homo sapiens (Human))		BDBM139530
PNG
(US8889708, 29)
Show SMILES Fc1cc(ccc1C[C@H](NC(=O)C12CCC(CC1)CN2)C#N)-c1cnn(CC2CCOCC2)c1 |r|
Show InChI InChI=1S/C26H32FN5O2/c27-24-12-20(22-15-30-32(17-22)16-19-5-9-34-10-6-19)1-2-21(24)11-23(13-28)31-25(33)26-7-3-18(4-8-26)14-29-26/h1-2,12,15,17-19,23,29H,3-11,14,16H2,(H,31,33)/t18?,23-,26?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 20.2n/an/an/an/an/a25



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys...

US Patent US8889708 (2014)


BindingDB Entry DOI: 10.7270/Q2JM28BB
More data for this
Ligand-Target Pair