BDBM155115 US9000183, 1
SMILES: CO[C@H]1CC[C@@]2(Cc3cc(C)c(Br)cc3C22N=C(C)C(N)=N2)CC1
InChI Key: InChIKey=VDSZYBZSHLIORQ-FGWLZILTSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-secretase 1 (Homo sapiens (Human)) | BDBM155115 (US9000183, 1) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a | 2.5 | n/a |
Astrazeneca AB US Patent | Assay Description The beta -secretase enzyme used in the TR-FRET is prepared as follows:The cDNA for the soluble part of the human beta -Secretase (AA 1-AA 460) was cl... | US Patent US9000183 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TQD | |||||||||||
More data for this Ligand-Target Pair |