null
SMILES: CC(C)C(=O)c1cnc2ccc(cc2c1Nc1ccc(nc1)N1CCNCC1)-c1cc(F)c(O)c(Cl)c1
InChI Key: InChIKey=VMHPJKQELDQLOV-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Maternal embryonic leucine zipper kinase (Homo sapiens (Human)) | BDBM177308 (US9120749, 674) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | 7.4 | 25 |
ONCOTHERAPY SCIENCE, INC. US Patent | Assay Description MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ... | US Patent US9120749 (2015) BindingDB Entry DOI: 10.7270/Q2FX7872 | |||||||||||
More data for this Ligand-Target Pair |