Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Maternal embryonic leucine zipper kinase' and Ligand = 'BDBM177308'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM177308 (US9120749, 674) Show SMILES CC(C)C(=O)c1cnc2ccc(cc2c1Nc1ccc(nc1)N1CCNCC1)-c1cc(F)c(O)c(Cl)c1 Show InChI InChI=1S/C28H27ClFN5O2/c1-16(2)27(36)21-15-32-24-5-3-17(18-12-22(29)28(37)23(30)13-18)11-20(24)26(21)34-19-4-6-25(33-14-19)35-9-7-31-8-10-35/h3-6,11-16,31,37H,7-10H2,1-2H3,(H,32,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.90	n/a	n/a	n/a	n/a	7.4	25
ONCOTHERAPY SCIENCE, INC. US Patent					Assay Description MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...				US Patent US9120749 (2015) BindingDB Entry DOI: 10.7270/Q2FX7872
					More data for this Ligand-Target Pair