BDBM193711 Pyrimidin-4-one-1,2,3-triazole conjugate, 3l

SMILES: Cn1c(SCc2cn(nn2)-c2cccnc2)nc(cc1=O)-c1ccccc1

InChI Key: InChIKey=QRJWBPDHJVCUTA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193711   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193711 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3l) Show SMILES Cn1c(SCc2cn(nn2)-c2cccnc2)nc(cc1=O)-c1ccccc1 Show InChI InChI=1S/C19H16N6OS/c1-24-18(26)10-17(14-6-3-2-4-7-14)21-19(24)27-13-15-12-25(23-22-15)16-8-5-9-20-11-16/h2-12H,13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 µL of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
					More data for this Ligand-Target Pair