BDBM196783 US9212178, 12
SMILES: Cc1nn(cc1CN1C[C@H](O)CO1)-c1ccnc(Nc2ccc3[nH]cc(C(=O)C4CC4)c3c2)n1
InChI Key:
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase SYK (Homo sapiens (Human)) | BDBM196783 (US9212178, 12) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13.5 | n/a | n/a | n/a | n/a | n/a | 25 |
Genosco; Oscotec, Inc. US Patent | Assay Description Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com... | US Patent US9212178 (2015) BindingDB Entry DOI: 10.7270/Q2X9294C | |||||||||||
More data for this Ligand-Target Pair |