BDBM196783 US9212178, 12

SMILES: Cc1nn(cc1CN1C[C@H](O)CO1)-c1ccnc(Nc2ccc3[nH]cc(C(=O)C4CC4)c3c2)n1

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196783   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM196783 (US9212178, 12) Show SMILES Cc1nn(cc1CN1C[C@H](O)CO1)-c1ccnc(Nc2ccc3[nH]cc(C(=O)C4CC4)c3c2)n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.5	n/a	n/a	n/a	n/a	n/a	25
Genosco; Oscotec, Inc. US Patent					Assay Description Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...				US Patent US9212178 (2015) BindingDB Entry DOI: 10.7270/Q2X9294C
					More data for this Ligand-Target Pair