BDBM201385 US9187424, 150

SMILES: Cc1cc(on1)C(=O)NC1=C(c2ccc(C)cc2)C(F)(F)C(NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F

InChI Key: InChIKey=QMBOXQGQNUDNLG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 201385   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201385 (US9187424, 150) Show SMILES Cc1cc(on1)C(=O)NC1=C(c2ccc(C)cc2)C(F)(F)C(NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F |c:10| Show InChI InChI=1S/C28H23F8N3O4/c1-15-4-6-17(7-5-15)21-22(37-23(40)20-14-16(2)39-43-20)24(41)38-26(27(21,32)33,28(34,35)36)18-8-10-19(11-9-18)42-13-3-12-25(29,30)31/h4-11,14H,3,12-13H2,1-2H3,(H,37,40)(H,38,41)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description MGAT2 enzyme was assayed using membranes isolated from Sf9 cells expressing the recombinant human MGAT2 cDNA with 2-monooleoylglycerol and [3H]-oleoy...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201385 (US9187424, 150) Show SMILES Cc1cc(on1)C(=O)NC1=C(c2ccc(C)cc2)C(F)(F)C(NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F |c:10| Show InChI InChI=1S/C28H23F8N3O4/c1-15-4-6-17(7-5-15)21-22(37-23(40)20-14-16(2)39-43-20)24(41)38-26(27(21,32)33,28(34,35)36)18-8-10-19(11-9-18)42-13-3-12-25(29,30)31/h4-11,14H,3,12-13H2,1-2H3,(H,37,40)(H,38,41)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair