BDBM209533 US9271969, 21

SMILES: OC(=O)C[C@H]1CCC(CC1)c1ccc(cc1)-c1ccc2nc(cn2c1)C(=O)NC1(CC1)c1cc(F)ccc1F

InChI Key: InChIKey=VZOSKDVNYJURRM-ULHFLLESSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209533   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM209533 (US9271969, 21) Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(cc1)-c1ccc2nc(cn2c1)C(=O)NC1(CC1)c1cc(F)ccc1F |r,wD:4.3,(11.21,-5.75,;9.88,-4.98,;9.88,-3.44,;8.55,-5.75,;7.21,-4.98,;7.21,-3.44,;5.88,-2.67,;4.55,-3.44,;4.55,-4.98,;5.88,-5.75,;3.21,-2.67,;1.88,-3.44,;.55,-2.67,;.55,-1.13,;1.88,-.36,;3.21,-1.13,;-.79,-.36,;-.79,1.18,;-2.12,1.95,;-3.46,1.18,;-4.92,1.66,;-5.82,.41,;-4.92,-.83,;-3.46,-.36,;-2.12,-1.13,;-7.36,.41,;-8.13,-.92,;-8.13,1.75,;-9.67,1.75,;-10.44,.41,;-11.21,1.75,;-8.9,3.08,;-7.36,3.08,;-6.59,4.41,;-5.05,4.41,;-7.36,5.75,;-8.9,5.75,;-9.67,4.41,;-11.21,4.41,)| Show InChI InChI=1S/C31H29F2N3O3/c32-24-10-11-26(33)25(16-24)31(13-14-31)35-30(39)27-18-36-17-23(9-12-28(36)34-27)22-7-5-21(6-8-22)20-3-1-19(2-4-20)15-29(37)38/h5-12,16-20H,1-4,13-15H2,(H,35,39)(H,37,38)/t19-,20?	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.4	25
KAINOS MEDICINE, INC. US Patent					Assay Description  Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ...				US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM209533 (US9271969, 21) Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(cc1)-c1ccc2nc(cn2c1)C(=O)NC1(CC1)c1cc(F)ccc1F |r,wD:4.3,(11.21,-5.75,;9.88,-4.98,;9.88,-3.44,;8.55,-5.75,;7.21,-4.98,;7.21,-3.44,;5.88,-2.67,;4.55,-3.44,;4.55,-4.98,;5.88,-5.75,;3.21,-2.67,;1.88,-3.44,;.55,-2.67,;.55,-1.13,;1.88,-.36,;3.21,-1.13,;-.79,-.36,;-.79,1.18,;-2.12,1.95,;-3.46,1.18,;-4.92,1.66,;-5.82,.41,;-4.92,-.83,;-3.46,-.36,;-2.12,-1.13,;-7.36,.41,;-8.13,-.92,;-8.13,1.75,;-9.67,1.75,;-10.44,.41,;-11.21,1.75,;-8.9,3.08,;-7.36,3.08,;-6.59,4.41,;-5.05,4.41,;-7.36,5.75,;-8.9,5.75,;-9.67,4.41,;-11.21,4.41,)| Show InChI InChI=1S/C31H29F2N3O3/c32-24-10-11-26(33)25(16-24)31(13-14-31)35-30(39)27-18-36-17-23(9-12-28(36)34-27)22-7-5-21(6-8-22)20-3-1-19(2-4-20)15-29(37)38/h5-12,16-20H,1-4,13-15H2,(H,35,39)(H,37,38)/t19-,20?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.4	25
KAINOS MEDICINE, INC. US Patent					Assay Description  Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ...				US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8
					More data for this Ligand-Target Pair