BDBM209534 US9271969, 22

SMILES: Cc1cccc(Cl)c1CNC(=O)c1cn2cc(ccc2n1)-c1ccc(cc1)C1CC[C@H](CC(O)=O)CC1

InChI Key: InChIKey=WJEVSAFBEYNYQB-ABOQPKSFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM209534 (US9271969, 22) Show SMILES Cc1cccc(Cl)c1CNC(=O)c1cn2cc(ccc2n1)-c1ccc(cc1)C1CC[C@H](CC(O)=O)CC1 |r,wD:30.34,(-10.83,2.41,;-10.06,3.75,;-10.83,5.08,;-10.06,6.41,;-8.52,6.41,;-7.75,5.08,;-6.21,5.08,;-8.52,3.75,;-7.75,2.41,;-8.52,1.08,;-7.75,-.25,;-8.52,-1.59,;-6.21,-.25,;-5.3,-1.5,;-3.84,-1.02,;-2.51,-1.79,;-1.17,-1.02,;-1.17,.52,;-2.51,1.29,;-3.84,.52,;-5.3,.99,;.16,-1.79,;.16,-3.33,;1.49,-4.1,;2.83,-3.33,;2.83,-1.79,;1.49,-1.02,;4.16,-4.1,;5.5,-3.33,;6.83,-4.1,;6.83,-5.64,;8.16,-6.41,;9.5,-5.64,;10.83,-6.41,;9.5,-4.1,;5.5,-6.41,;4.16,-5.64,)| Show InChI InChI=1S/C30H30ClN3O3/c1-19-3-2-4-26(31)25(19)16-32-30(37)27-18-34-17-24(13-14-28(34)33-27)23-11-9-22(10-12-23)21-7-5-20(6-8-21)15-29(35)36/h2-4,9-14,17-18,20-21H,5-8,15-16H2,1H3,(H,32,37)(H,35,36)/t20-,21?	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.60	n/a	n/a	n/a	n/a	7.4	25
KAINOS MEDICINE, INC. US Patent					Assay Description  Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ...				US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM209534 (US9271969, 22) Show SMILES Cc1cccc(Cl)c1CNC(=O)c1cn2cc(ccc2n1)-c1ccc(cc1)C1CC[C@H](CC(O)=O)CC1 |r,wD:30.34,(-10.83,2.41,;-10.06,3.75,;-10.83,5.08,;-10.06,6.41,;-8.52,6.41,;-7.75,5.08,;-6.21,5.08,;-8.52,3.75,;-7.75,2.41,;-8.52,1.08,;-7.75,-.25,;-8.52,-1.59,;-6.21,-.25,;-5.3,-1.5,;-3.84,-1.02,;-2.51,-1.79,;-1.17,-1.02,;-1.17,.52,;-2.51,1.29,;-3.84,.52,;-5.3,.99,;.16,-1.79,;.16,-3.33,;1.49,-4.1,;2.83,-3.33,;2.83,-1.79,;1.49,-1.02,;4.16,-4.1,;5.5,-3.33,;6.83,-4.1,;6.83,-5.64,;8.16,-6.41,;9.5,-5.64,;10.83,-6.41,;9.5,-4.1,;5.5,-6.41,;4.16,-5.64,)| Show InChI InChI=1S/C30H30ClN3O3/c1-19-3-2-4-26(31)25(19)16-32-30(37)27-18-34-17-24(13-14-28(34)33-27)23-11-9-22(10-12-23)21-7-5-20(6-8-21)15-29(35)36/h2-4,9-14,17-18,20-21H,5-8,15-16H2,1H3,(H,32,37)(H,35,36)/t20-,21?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.7	n/a	n/a	n/a	n/a	7.4	25
KAINOS MEDICINE, INC. US Patent					Assay Description  Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ...				US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8
					More data for this Ligand-Target Pair