BDBM209568 US9271969, 56

SMILES: OC(=O)C[C@H]1CCC(CC1)c1ccc(cc1)-c1cn2cc(nc2s1)C(=O)NCc1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=IALTYDHGZCHKJE-VYOWRKJJSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM209568 (US9271969, 56) Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(cc1)-c1cn2cc(nc2s1)C(=O)NCc1ccc(OC(F)(F)F)cc1 |r,wD:4.3,(12.38,3.33,;10.84,3.33,;10.07,4.67,;10.07,2,;8.53,2,;7.76,3.33,;6.22,3.33,;5.45,2,;6.22,.67,;7.76,.67,;3.91,2,;3.14,.67,;1.6,.67,;.83,2,;1.6,3.33,;3.14,3.33,;-.71,2,;-1.62,.75,;-3.08,1.23,;-4.54,.75,;-5.45,2,;-4.54,3.25,;-3.08,2.77,;-1.62,3.25,;-6.99,2,;-7.76,3.33,;-7.76,.67,;-9.3,.67,;-10.07,-.67,;-9.3,-2,;-10.07,-3.33,;-11.61,-3.33,;-12.38,-4.67,;-13.87,-5.07,;-15.35,-5.47,;-13.47,-6.55,;-13.87,-3.53,;-12.38,-2,;-11.61,-.67,)| Show InChI InChI=1S/C28H26F3N3O4S/c29-28(30,31)38-22-11-3-18(4-12-22)14-32-26(37)23-15-34-16-24(39-27(34)33-23)21-9-7-20(8-10-21)19-5-1-17(2-6-19)13-25(35)36/h3-4,7-12,15-17,19H,1-2,5-6,13-14H2,(H,32,37)(H,35,36)/t17-,19?	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.4	25
KAINOS MEDICINE, INC. US Patent					Assay Description  Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ...				US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM209568 (US9271969, 56) Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(cc1)-c1cn2cc(nc2s1)C(=O)NCc1ccc(OC(F)(F)F)cc1 |r,wD:4.3,(12.38,3.33,;10.84,3.33,;10.07,4.67,;10.07,2,;8.53,2,;7.76,3.33,;6.22,3.33,;5.45,2,;6.22,.67,;7.76,.67,;3.91,2,;3.14,.67,;1.6,.67,;.83,2,;1.6,3.33,;3.14,3.33,;-.71,2,;-1.62,.75,;-3.08,1.23,;-4.54,.75,;-5.45,2,;-4.54,3.25,;-3.08,2.77,;-1.62,3.25,;-6.99,2,;-7.76,3.33,;-7.76,.67,;-9.3,.67,;-10.07,-.67,;-9.3,-2,;-10.07,-3.33,;-11.61,-3.33,;-12.38,-4.67,;-13.87,-5.07,;-15.35,-5.47,;-13.47,-6.55,;-13.87,-3.53,;-12.38,-2,;-11.61,-.67,)| Show InChI InChI=1S/C28H26F3N3O4S/c29-28(30,31)38-22-11-3-18(4-12-22)14-32-26(37)23-15-34-16-24(39-27(34)33-23)21-9-7-20(8-10-21)19-5-1-17(2-6-19)13-25(35)36/h3-4,7-12,15-17,19H,1-2,5-6,13-14H2,(H,32,37)(H,35,36)/t17-,19?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.4	25
KAINOS MEDICINE, INC. US Patent					Assay Description  Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ...				US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8
					More data for this Ligand-Target Pair