BDBM209577 US9271969, 65

SMILES: CC(C)([C@H]1CCC(CC1)c1ccc(cc1)-c1ccc2nc(cn2c1)C(=O)NCc1ccccc1)C(O)=O

InChI Key: InChIKey=NCQLXEQRKGLRFK-OMWPTYOUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209577   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM209577 (US9271969, 65) Show SMILES CC(C)([C@H]1CCC(CC1)c1ccc(cc1)-c1ccc2nc(cn2c1)C(=O)NCc1ccccc1)C(O)=O |r,wD:3.2,(8.55,-6.41,;9.32,-5.08,;10.09,-6.41,;7.98,-4.31,;7.98,-2.77,;6.65,-2,;5.32,-2.77,;5.32,-4.31,;6.65,-5.08,;3.98,-2,;2.65,-2.77,;1.32,-2,;1.32,-.46,;2.65,.31,;3.98,-.46,;-.02,.31,;-.02,1.85,;-1.35,2.62,;-2.69,1.85,;-4.15,2.33,;-5.06,1.08,;-4.15,-.17,;-2.69,.31,;-1.35,-.46,;-6.6,1.08,;-7.37,-.25,;-7.37,2.41,;-8.91,2.41,;-9.68,3.75,;-8.91,5.08,;-9.68,6.41,;-11.22,6.41,;-11.99,5.08,;-11.22,3.75,;10.65,-4.31,;11.99,-5.08,;10.65,-2.77,)| Show InChI InChI=1S/C31H33N3O3/c1-31(2,30(36)37)26-15-12-23(13-16-26)22-8-10-24(11-9-22)25-14-17-28-33-27(20-34(28)19-25)29(35)32-18-21-6-4-3-5-7-21/h3-11,14,17,19-20,23,26H,12-13,15-16,18H2,1-2H3,(H,32,35)(H,36,37)/t23?,26-	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<125	n/a	n/a	n/a	n/a	7.4	25
KAINOS MEDICINE, INC. US Patent					Assay Description  Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ...				US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM209577 (US9271969, 65) Show SMILES CC(C)([C@H]1CCC(CC1)c1ccc(cc1)-c1ccc2nc(cn2c1)C(=O)NCc1ccccc1)C(O)=O |r,wD:3.2,(8.55,-6.41,;9.32,-5.08,;10.09,-6.41,;7.98,-4.31,;7.98,-2.77,;6.65,-2,;5.32,-2.77,;5.32,-4.31,;6.65,-5.08,;3.98,-2,;2.65,-2.77,;1.32,-2,;1.32,-.46,;2.65,.31,;3.98,-.46,;-.02,.31,;-.02,1.85,;-1.35,2.62,;-2.69,1.85,;-4.15,2.33,;-5.06,1.08,;-4.15,-.17,;-2.69,.31,;-1.35,-.46,;-6.6,1.08,;-7.37,-.25,;-7.37,2.41,;-8.91,2.41,;-9.68,3.75,;-8.91,5.08,;-9.68,6.41,;-11.22,6.41,;-11.99,5.08,;-11.22,3.75,;10.65,-4.31,;11.99,-5.08,;10.65,-2.77,)| Show InChI InChI=1S/C31H33N3O3/c1-31(2,30(36)37)26-15-12-23(13-16-26)22-8-10-24(11-9-22)25-14-17-28-33-27(20-34(28)19-25)29(35)32-18-21-6-4-3-5-7-21/h3-11,14,17,19-20,23,26H,12-13,15-16,18H2,1-2H3,(H,32,35)(H,36,37)/t23?,26-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.4	25
KAINOS MEDICINE, INC. US Patent					Assay Description  Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ...				US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8
					More data for this Ligand-Target Pair