null
SMILES: Cc1csc(NC(=O)c2cc(cn3ncnc23)-c2cc3ccccc3o2)n1
InChI Key: InChIKey=HURYMOWTLPRIHL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat)) | BDBM211663 (US9550778, chem-us-00203) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >10 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Vanderbilt University US Patent | Assay Description The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec... | US Patent US9550778 (2017) BindingDB Entry DOI: 10.7270/Q24M96J4 | |||||||||||
More data for this Ligand-Target Pair |