Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM211663'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM211663 (US9550778, chem-us-00203) Show SMILES Cc1csc(NC(=O)c2cc(cn3ncnc23)-c2cc3ccccc3o2)n1 Show InChI InChI=1S/C19H13N5O2S/c1-11-9-27-19(22-11)23-18(25)14-6-13(8-24-17(14)20-10-21-24)16-7-12-4-2-3-5-15(12)26-16/h2-10H,1H3,(H,22,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>10	n/a	n/a	n/a	n/a	7.4	25
Vanderbilt University US Patent					Assay Description The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...				US Patent US9550778 (2017) BindingDB Entry DOI: 10.7270/Q24M96J4
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