null

SMILES: C=C(CCN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)c1ccccc1

InChI Key: InChIKey=BEEXRDPWWKFYAY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22185   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22185 (1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylbut-3-en-1...) Show SMILES C=C(CCN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C29H34N2O/c1-25(26-11-5-2-6-12-26)17-18-30-19-21-31(22-20-30)23-24-32-29(27-13-7-3-8-14-27)28-15-9-4-10-16-28/h2-16,29H,1,17-24H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	30	-9.53	n/a	n/a	n/a	n/a	n/a	7.4	4
National Taiwan University					Assay Description The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...				J Med Chem 51: 2795-806 (2008) Article DOI: 10.1021/jm701270n BindingDB Entry DOI: 10.7270/Q2B27SK6
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM22185 (1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylbut-3-en-1...) Show SMILES C=C(CCN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C29H34N2O/c1-25(26-11-5-2-6-12-26)17-18-30-19-21-31(22-20-30)23-24-32-29(27-13-7-3-8-14-27)28-15-9-4-10-16-28/h2-16,29H,1,17-24H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...				J Med Chem 51: 2795-806 (2008) Article DOI: 10.1021/jm701270n BindingDB Entry DOI: 10.7270/Q2B27SK6
					More data for this Ligand-Target Pair