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BDBM222383 IPR-1160 (36)

SMILES: OC1=C(C(N(C1=O)c1ccc2ncccc2c1)c1cccc(F)c1)C(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=URWQIMGHHBPVHY-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222383   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Urokinase receptor (uPAR)


(Homo sapiens (Human))		BDBM222383
PNG
(IPR-1160 (36))
Show SMILES OC1=C(C(N(C1=O)c1ccc2ncccc2c1)c1cccc(F)c1)C(=O)c1ccc(Cl)cc1 |t:1|
Show InChI InChI=1S/C26H16ClFN2O3/c27-18-8-6-15(7-9-18)24(31)22-23(17-3-1-5-19(28)13-17)30(26(33)25(22)32)20-10-11-21-16(14-20)4-2-12-29-21/h1-14,23,32H
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 1.90E+3n/an/an/an/an/an/an/an/a



Indiana University School of Medicine



Assay Description
Polarized fluorescence intensities were measured using an EnVision Multilabel plate reader (PerkinElmer) with excitation and emission wavelengths of ...

Biochemistry 56: 1768-1784 (2017)


Article DOI: 10.1021/acs.biochem.6b01039
BindingDB Entry DOI: 10.7270/Q2NS0SQC
More data for this
Ligand-Target Pair