BindingDB logo
myBDB logout

null

SMILES: CCOC(=O)CSc1nc2ccc(Cl)cc2c(=O)n1-c1ccc(OC)cc1

InChI Key: InChIKey=IGLJWNMDPHMKQH-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 226160   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydrofolate reductase


(Bos taurus (Cattle))		BDBM226160
PNG
(Ethyl 2-(6-chloro-3-(4-methoxyphenyl)-4-oxo-3,4-di...)
Show SMILES CCOC(=O)CSc1nc2ccc(Cl)cc2c(=O)n1-c1ccc(OC)cc1
Show InChI InChI=1S/C19H17ClN2O4S/c1-3-26-17(23)11-27-19-21-16-9-4-12(20)10-15(16)18(24)22(19)13-5-7-14(25-2)8-6-13/h4-10H,3,11H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 1.70E+3n/an/an/an/a7.425



Future University



Assay Description
The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...

Bioorg Chem 72: 282-292 (2017)


BindingDB Entry DOI: 10.7270/Q2TX3D82
More data for this
Ligand-Target Pair