BDBM235571 US9359338, Exe. 181
SMILES: CC(F)(F)c1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c1
InChI Key: InChIKey=MDNLKYRIJOCOMZ-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM235571 (US9359338, Exe. 181) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | 30 |
CROWN BIOSCIENCE INC. (Taiwan) US Patent | Assay Description [Experimental method]: Use ADP-GLO™ assay kit from Promega to evaluate the inhibitory activity of compounds at B-Raf. [Instrument]: PerKinElmer... | US Patent US9359338 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M7N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (VEGFR2) (Homo sapiens (Human)) | BDBM235571 (US9359338, Exe. 181) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | 30 |
CROWN BIOSCIENCE INC. (Taiwan) US Patent | Assay Description [Experimental method]: Use Lance@Ultra Ulight™-TK assay kit from PerKinElmer to evaluate the inhibitory activity of compounds at KDR kinase. [I... | US Patent US9359338 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M7N | |||||||||||
More data for this Ligand-Target Pair |