Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM235571'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM235571 (US9359338, Exe. 181) Show SMILES CC(F)(F)c1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c1 Show InChI InChI=1S/C24H20F4N4O3/c1-24(27,28)14-4-6-17(25)19(10-14)31-23(34)30-15-5-7-20(18(26)11-15)35-16-8-9-29-21(12-16)32-22(33)13-2-3-13/h4-13H,2-3H2,1H3,(H,29,32,33)(H2,30,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	30
CROWN BIOSCIENCE INC. (Taiwan) US Patent					Assay Description [Experimental method]: Use ADP-GLO™ assay kit from Promega to evaluate the inhibitory activity of compounds at B-Raf. [Instrument]: PerKinElmer...				US Patent US9359338 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M7N
					More data for this Ligand-Target Pair