null
SMILES: OCCOc1ccc(c(F)c1)-c1cc2c(c[nH]c2cc1Cl)C(O)=O
InChI Key: InChIKey=LJGJSCKLAYLZFG-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human)) | BDBM238002 (US9394285, 86) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 99.2 | n/a | n/a | 7.5 | 25 |
Pfizer Inc. US Patent | Assay Description The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass... | US Patent US9394285 (2016) BindingDB Entry DOI: 10.7270/Q2DB80Q7 | |||||||||||
More data for this Ligand-Target Pair |