Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1' and Ligand = 'BDBM238002'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM238002 (US9394285, 86) Show SMILES OCCOc1ccc(c(F)c1)-c1cc2c(c[nH]c2cc1Cl)C(O)=O Show InChI InChI=1S/C17H13ClFNO4/c18-14-7-16-12(13(8-20-16)17(22)23)6-11(14)10-2-1-9(5-15(10)19)24-4-3-21/h1-2,5-8,20-21H,3-4H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	99.2	n/a	n/a	7.5	25
Pfizer Inc. US Patent					Assay Description The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...				US Patent US9394285 (2016) BindingDB Entry DOI: 10.7270/Q2DB80Q7
					More data for this Ligand-Target Pair