BDBM2564 2-(3,4-dihydroxy-5-oxo-2,5-dihydrofuran-2-yl)-2-hydroxyethyl 5-cyclohexylpentanoate::Parke-Davis compound 7

SMILES: OC(COC(=O)CCCCC1CCCCC1)C1OC(=O)C(O)C1=O

InChI Key: InChIKey=LFDGQBHODLGSBR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2564   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 Protease (Human immunodeficiency virus type 1)	BDBM2564 (2-(3,4-dihydroxy-5-oxo-2,5-dihydrofuran-2-yl)-2-hy...) Show SMILES OC(COC(=O)CCCCC1CCCCC1)C1OC(=O)C(O)C1=O Show InChI InChI=1S/C17H26O7/c18-12(16-14(20)15(21)17(22)24-16)10-23-13(19)9-5-4-8-11-6-2-1-3-7-11/h11-12,15-16,18,21H,1-10H2	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	4.7	37
Parke-Davis Pharmaceutical Research					Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...				Bioorg Med Chem 4: 1401-10 (1996) Article DOI: 10.1016/j.bmcl.2004.12.068 BindingDB Entry DOI: 10.7270/Q2PZ571Q
					More data for this Ligand-Target Pair