BDBM2570 4-hydroxy-6-(4-hydroxyphenyl)-3-[(2-phenylethyl)sulfanyl]-2H-pyran-2-one::4-hydroxy-6-phenylpyranone 18

SMILES: Oc1ccc(cc1)-c1cc(O)c(SCCc2ccccc2)c(=O)o1

InChI Key: InChIKey=NNMBWFBLHKMVSF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 Protease (Human immunodeficiency virus type 1)	BDBM2570 (4-hydroxy-6-(4-hydroxyphenyl)-3-[(2-phenylethyl)su...) Show SMILES Oc1ccc(cc1)-c1cc(O)c(SCCc2ccccc2)c(=O)o1 Show InChI InChI=1S/C19H16O4S/c20-15-8-6-14(7-9-15)17-12-16(21)18(19(22)23-17)24-11-10-13-4-2-1-3-5-13/h1-9,12,20-21H,10-11H2	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	4.7	37
Parke-Davis Pharmaceutical Research					Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...				Bioorg Med Chem 4: 1401-10 (1996) Article DOI: 10.1016/j.bmcl.2004.12.068 BindingDB Entry DOI: 10.7270/Q2PZ571Q
					More data for this Ligand-Target Pair