BDBM26075 2-benzyl-3-aryl-7-trifluoromethylindazole, 21::3-(4-chlorophenyl)-7-(trifluoromethyl)-2-{[2-(trifluoromethyl)phenyl]methyl}-2H-indazole

SMILES: FC(F)(F)c1ccccc1Cn1nc2c(cccc2c1-c1ccc(Cl)cc1)C(F)(F)F

InChI Key: InChIKey=CDLBQZJYZMCUBN-UHFFFAOYSA-N

Data: 2 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26075   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Liver X Receptor alpha (LXR-alpha) (Homo sapiens (Human))	BDBM26075 (2-benzyl-3-aryl-7-trifluoromethylindazole, 21 | 3-...) Show SMILES FC(F)(F)c1ccccc1Cn1nc2c(cccc2c1-c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C22H13ClF6N2/c23-15-10-8-13(9-11-15)20-16-5-3-7-18(22(27,28)29)19(16)30-31(20)12-14-4-1-2-6-17(14)21(24,25)26/h1-11H,12H2	PDB MMDB Reactome pathway B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	465	n/a	1.58E+4	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair
Liver X Receptor beta (LXR-beta) (Homo sapiens (Human))	BDBM26075 (2-benzyl-3-aryl-7-trifluoromethylindazole, 21 | 3-...) Show SMILES FC(F)(F)c1ccccc1Cn1nc2c(cccc2c1-c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C22H13ClF6N2/c23-15-10-8-13(9-11-15)20-16-5-3-7-18(22(27,28)29)19(16)30-31(20)12-14-4-1-2-6-17(14)21(24,25)26/h1-11H,12H2	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	1.55E+4	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair