BDBM276134 2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methoxy]-5-methoxy-::US10071988, Example 41::US10233173, Example 41

SMILES: COc1cnc(OCc2cn(nn2)-c2ccc(F)c(Br)c2)nc1

InChI Key: InChIKey=BQSLLRKTYVRHJA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 276134   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GluN1/GluN2B NMDA receptor (Homo sapiens (Human))	BDBM276134 (2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methox...) Show SMILES COc1cnc(OCc2cn(nn2)-c2ccc(F)c(Br)c2)nc1 Show InChI InChI=1S/C14H11BrFN5O2/c1-22-11-5-17-14(18-6-11)23-8-9-7-21(20-19-9)10-2-3-13(16)12(15)4-10/h2-7H,8H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Lund University					Assay Description NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...				Bioorg Med Chem 14: 1215-20 (2006) BindingDB Entry DOI: 10.7270/Q23R0W6K
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM276134 (2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methox...) Show SMILES COc1cnc(OCc2cn(nn2)-c2ccc(F)c(Br)c2)nc1 Show InChI InChI=1S/C14H11BrFN5O2/c1-22-11-5-17-14(18-6-11)23-8-9-7-21(20-19-9)10-2-3-13(16)12(15)4-10/h2-7H,8H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.4	25
JANSSEN PHARMACEUTICA NV US Patent					Assay Description NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...				US Patent US10071988 (2018) BindingDB Entry DOI: 10.7270/Q20Z7591
					More data for this Ligand-Target Pair