BDBM280382 US10030012, Example 12::ethyl 4-[4-(5- methyl-1H- pyrazol-1- yl)piperidin-1- yl]azepane-1- carboxylate

SMILES: CCOC(=O)N1CCCC(CC1)N1CCC(CC1)n1nccc1C

InChI Key: InChIKey=DKTIHUPDSBUGTH-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 280382   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM280382 (US10030012, Example 12 | ethyl 4-[4-(5- methyl-1H-...) Show SMILES CCOC(=O)N1CCCC(CC1)N1CCC(CC1)n1nccc1C Show InChI InChI=1S/C18H30N4O2/c1-3-24-18(23)21-11-4-5-16(7-14-21)20-12-8-17(9-13-20)22-15(2)6-10-19-22/h6,10,16-17H,3-5,7-9,11-14H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+7	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent									US Patent US10030012 (2018) BindingDB Entry DOI: 10.7270/Q2KK9DTW
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM280382 (US10030012, Example 12 | ethyl 4-[4-(5- methyl-1H-...) Show SMILES CCOC(=O)N1CCCC(CC1)N1CCC(CC1)n1nccc1C Show InChI InChI=1S/C18H30N4O2/c1-3-24-18(23)21-11-4-5-16(7-14-21)20-12-8-17(9-13-20)22-15(2)6-10-19-22/h6,10,16-17H,3-5,7-9,11-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	520	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...				US Patent US10030012 (2018) BindingDB Entry DOI: 10.7270/Q2KK9DTW
					More data for this Ligand-Target Pair