null
SMILES: CN1CCN(CC1)Oc1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
InChI Key: InChIKey=GYIJTRBMHLZMET-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM301794![]() (N-[6-(2-Benzyloxy) 1H-indazol-3-yl]-4-(1-methyl-pi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
NERVIANO MEDICAL SCIENCES S.R.L. US Patent | Assay Description i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ... | US Patent US9597317 (2017) BindingDB Entry DOI: 10.7270/Q2N58PDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM301794![]() (N-[6-(2-Benzyloxy) 1H-indazol-3-yl]-4-(1-methyl-pi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
NERVIANO MEDICAL SCIENCES S.R.L. US Patent | Assay Description i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p... | US Patent US9597317 (2017) BindingDB Entry DOI: 10.7270/Q2N58PDX | |||||||||||
More data for this Ligand-Target Pair |