null

SMILES: OC(=O)c1ccc(NC(=O)Cn2cc3c(cc2=O)-c2cc(Cl)ccc2CCNC3=O)cc1

InChI Key: InChIKey=YHCVQIPIKWVWDD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 303786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasma kallikrein (Homo sapiens (Human))	BDBM303786 (4-{[(11-Chloro-2,5-dioxo-5,6,7,8-tetrahydropyrido[...) Show SMILES OC(=O)c1ccc(NC(=O)Cn2cc3c(cc2=O)-c2cc(Cl)ccc2CCNC3=O)cc1 |$;;;;;;;HN;;;;;;;;;;;;;;;;;;;;HN;;;;$| Show InChI InChI=1S/C23H18ClN3O5/c24-15-4-1-13-7-8-25-22(30)19-11-27(21(29)10-18(19)17(13)9-15)12-20(28)26-16-5-2-14(3-6-16)23(31)32/h1-6,9-11H,7-8,12H2,(H,25,30)(H,26,28)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...				US Patent US10138236 (2018) BindingDB Entry DOI: 10.7270/Q2445PH4
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM303786 (4-{[(11-Chloro-2,5-dioxo-5,6,7,8-tetrahydropyrido[...) Show SMILES OC(=O)c1ccc(NC(=O)Cn2cc3c(cc2=O)-c2cc(Cl)ccc2CCNC3=O)cc1 |$;;;;;;;HN;;;;;;;;;;;;;;;;;;;;HN;;;;$| Show InChI InChI=1S/C23H18ClN3O5/c24-15-4-1-13-7-8-25-22(30)19-11-27(21(29)10-18(19)17(13)9-15)12-20(28)26-16-5-2-14(3-6-16)23(31)32/h1-6,9-11H,7-8,12H2,(H,25,30)(H,26,28)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...				US Patent US10138236 (2018) BindingDB Entry DOI: 10.7270/Q2445PH4
					More data for this Ligand-Target Pair