null

SMILES: CCOc1ccc(cc1C)-c1[nH]c(nc1C)C1(CC)CCN(CC1)c1ncnc2[nH]c(C)cc12

InChI Key: InChIKey=IDVWQQKQWJFOAS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit [D816V] (Homo sapiens (Human))	BDBM342310 (4-[4-[5-(4-ethoxy-3-methyl-phenyl)-4- methyl-1H-im...) Show SMILES CCOc1ccc(cc1C)-c1[nH]c(nc1C)C1(CC)CCN(CC1)c1ncnc2[nH]c(C)cc12 Show InChI InChI=1S/C27H34N6O/c1-6-27(10-12-33(13-11-27)25-21-15-18(4)30-24(21)28-16-29-25)26-31-19(5)23(32-26)20-8-9-22(34-7-2)17(3)14-20/h8-9,14-16H,6-7,10-13H2,1-5H3,(H,31,32)(H,28,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...				US Patent US9771369 (2017) BindingDB Entry DOI: 10.7270/Q24J0H7Q
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM342310 (4-[4-[5-(4-ethoxy-3-methyl-phenyl)-4- methyl-1H-im...) Show SMILES CCOc1ccc(cc1C)-c1[nH]c(nc1C)C1(CC)CCN(CC1)c1ncnc2[nH]c(C)cc12 Show InChI InChI=1S/C27H34N6O/c1-6-27(10-12-33(13-11-27)25-21-15-18(4)30-24(21)28-16-29-25)26-31-19(5)23(32-26)20-8-9-22(34-7-2)17(3)14-20/h8-9,14-16H,6-7,10-13H2,1-5H3,(H,31,32)(H,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...				US Patent US9771369 (2017) BindingDB Entry DOI: 10.7270/Q24J0H7Q
					More data for this Ligand-Target Pair