null

SMILES: COc1cccc(c1)[C@H](C)NC(=O)N1C2CCC1CN(C2)c1ncnc2cc(sc12)-c1ccc(F)cc1

InChI Key: InChIKey=FKJKEKKFAAAJHX-YTXWROIDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 369253   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit [D816V] (Homo sapiens (Human))	BDBM369253 (3-[6-(4-fluorophenyl)thieno[3,2- d]pyrimidin-4-yl]...) Show SMILES COc1cccc(c1)[C@H](C)NC(=O)N1C2CCC1CN(C2)c1ncnc2cc(sc12)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C28H28FN5O2S/c1-17(19-4-3-5-23(12-19)36-2)32-28(35)34-21-10-11-22(34)15-33(14-21)27-26-24(30-16-31-27)13-25(37-26)18-6-8-20(29)9-7-18/h3-9,12-13,16-17,21-22H,10-11,14-15H2,1-2H3,(H,32,35)/t17-,21?,22?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universitàadi Roma					Assay Description The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...				J Med Chem 51: 1560-76 (2008) BindingDB Entry DOI: 10.7270/Q2HX1FZW
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM369253 (3-[6-(4-fluorophenyl)thieno[3,2- d]pyrimidin-4-yl]...) Show SMILES COc1cccc(c1)[C@H](C)NC(=O)N1C2CCC1CN(C2)c1ncnc2cc(sc12)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C28H28FN5O2S/c1-17(19-4-3-5-23(12-19)36-2)32-28(35)34-21-10-11-22(34)15-33(14-21)27-26-24(30-16-31-27)13-25(37-26)18-6-8-20(29)9-7-18/h3-9,12-13,16-17,21-22H,10-11,14-15H2,1-2H3,(H,32,35)/t17-,21?,22?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universitàadi Roma					Assay Description The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...				J Med Chem 51: 1560-76 (2008) BindingDB Entry DOI: 10.7270/Q2HX1FZW
					More data for this Ligand-Target Pair