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SMILES: C[C@H](NC(C)=O)\C=C(/F)[C@@H]1CC[C@H](CO1)Oc1nc2c(F)cc(OCC(F)F)c(F)c2n1C

InChI Key: InChIKey=ONTRBHHRFLYYGE-DGPCQLGMSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369710   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))		BDBM369710
PNG
(US10233156, Example I-250)
Show SMILES C[C@H](NC(C)=O)\C=C(/F)[C@@H]1CC[C@H](CO1)Oc1nc2c(F)cc(OCC(F)F)c(F)c2n1C |r|
Show InChI InChI=1S/C21H24F5N3O4/c1-10(27-11(2)30)6-13(22)15-5-4-12(8-31-15)33-21-28-19-14(23)7-16(32-9-17(24)25)18(26)20(19)29(21)3/h6-7,10,12,15,17H,4-5,8-9H2,1-3H3,(H,27,30)/b13-6-/t10-,12+,15-/m0/s1
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n/an/a 21n/an/an/an/an/an/a



Abbott Laboratories



Assay Description
Recombinant human ACC1 and recombinant human ACC2, which were prepared by the method mentioned above, were preincubated with assay buffer solution (5...

J Med Chem 50: 641-62 (2007)


BindingDB Entry DOI: 10.7270/Q2C53P4Z
More data for this
Ligand-Target Pair