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BDBM384730 US10285983, Compound 43

SMILES: Fc1ccc(cc1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2ncc(cc12)-c1cncc(CN2CCCCC2)c1

InChI Key: InChIKey=BGYIOCGHSKJPBS-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384730   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384730
PNG
(US10285983, Compound 43)
Show SMILES Fc1ccc(cc1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2ncc(cc12)-c1cncc(CN2CCCCC2)c1
Show InChI InChI=1S/C30H26FN7/c31-23-6-4-20(5-7-23)24-8-9-33-29-25(24)14-27(35-29)28-26-13-22(17-34-30(26)37-36-28)21-12-19(15-32-16-21)18-38-10-2-1-3-11-38/h4-9,12-17H,1-3,10-11,18H2,(H,33,35)(H,34,36,37)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair