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SMILES: Fc1cccnc1C(=O)Nc1cnc2[nH]c(cc2c1)-c1ccccc1

InChI Key: InChIKey=OGHINACKYAIADY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392367   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit [D816V] (Homo sapiens (Human))	BDBM392367 (3-fluoro-N-(2-phenyl-1H-pyrrolo [2,3-b]pyridin-5-y...) Show SMILES Fc1cccnc1C(=O)Nc1cnc2[nH]c(cc2c1)-c1ccccc1 Show InChI InChI=1S/C19H13FN4O/c20-15-7-4-8-21-17(15)19(25)23-14-9-13-10-16(24-18(13)22-11-14)12-5-2-1-3-6-12/h1-11H,(H,22,24)(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...				J Med Chem 52: 1799-802 (2009) BindingDB Entry DOI: 10.7270/Q2HH6NDZ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM392367 (3-fluoro-N-(2-phenyl-1H-pyrrolo [2,3-b]pyridin-5-y...) Show SMILES Fc1cccnc1C(=O)Nc1cnc2[nH]c(cc2c1)-c1ccccc1 Show InChI InChI=1S/C19H13FN4O/c20-15-7-4-8-21-17(15)19(25)23-14-9-13-10-16(24-18(13)22-11-14)12-5-2-1-3-6-12/h1-11H,(H,22,24)(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...				J Med Chem 52: 1799-802 (2009) BindingDB Entry DOI: 10.7270/Q2HH6NDZ
					More data for this Ligand-Target Pair