null

SMILES: CCc1ccc(cn1)-c1cc2cc(NC(=O)c3[nH]nc(C)c3C)cnc2[nH]1

InChI Key: InChIKey=PBWBGJWUVLDITB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392472   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM392472 (N-[2-(6-ethyl-3-pyridyl)-1H- pyrrolo[2,3-b]pyridin...) Show SMILES CCc1ccc(cn1)-c1cc2cc(NC(=O)c3[nH]nc(C)c3C)cnc2[nH]1 Show InChI InChI=1S/C20H20N6O/c1-4-15-6-5-13(9-21-15)17-8-14-7-16(10-22-19(14)24-17)23-20(27)18-11(2)12(3)25-26-18/h5-10H,4H2,1-3H3,(H,22,24)(H,23,27)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...				J Med Chem 52: 1799-802 (2009) BindingDB Entry DOI: 10.7270/Q2HH6NDZ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [D816V] (Homo sapiens (Human))	BDBM392472 (N-[2-(6-ethyl-3-pyridyl)-1H- pyrrolo[2,3-b]pyridin...) Show SMILES CCc1ccc(cn1)-c1cc2cc(NC(=O)c3[nH]nc(C)c3C)cnc2[nH]1 Show InChI InChI=1S/C20H20N6O/c1-4-15-6-5-13(9-21-15)17-8-14-7-16(10-22-19(14)24-17)23-20(27)18-11(2)12(3)25-26-18/h5-10H,4H2,1-3H3,(H,22,24)(H,23,27)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...				J Med Chem 52: 1799-802 (2009) BindingDB Entry DOI: 10.7270/Q2HH6NDZ
					More data for this Ligand-Target Pair