BDBM397924 US9994552, Compound 135
SMILES: CCOc1cc2ncnc(N3CCN(CC3)c3ncc(Cc4ccccc4)c(N)n3)c2cc1OCC1CCN(C)CC1
InChI Key: InChIKey=XIOMZYRSUVDTKC-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase Kit (Kit)(D816V) (Homo sapiens (Human)) | BDBM397924 (US9994552, Compound 135) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University | Assay Description Kit D816V assay: In each well of a 384-well plate, 0.04 ng/ul (0.5 nM) of D816V Kit (Carna Bioscience 08-156) was incubated in a total of 12.5 ul of ... | J Med Chem 52: 4892-902 (2009) BindingDB Entry DOI: 10.7270/Q27M0B8Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM397924 (US9994552, Compound 135) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University | Assay Description Kit wild type assay: In each well of a 384-well plate, 0.2 ng/ul final (2 nM) of wild type Kit (Carna Bioscience 08-156) was incubated in a total of ... | J Med Chem 52: 4892-902 (2009) BindingDB Entry DOI: 10.7270/Q27M0B8Q | |||||||||||
More data for this Ligand-Target Pair |