BDBM40622 MLS000053340::N-(2-furanylmethyl)-2,3-dihydro-1H-cyclopenta[b]quinoline-9-carboxamide::N-(2-furfuryl)-2,3-dihydro-1H-cyclopenta[b]quinoline-9-carboxamide::N-(furan-2-ylmethyl)-2,3-dihydro-1H-cyclopenta[b]quinoline-9-carboxamide::SMR000067677::cid_862194

SMILES: O=C(NCc1ccco1)c1c2CCCc2nc2ccccc12

InChI Key: InChIKey=MWKFPUUBWYOUJG-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 40622   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
nuclear receptor subfamily 4, group A, member 1 (Homo sapiens (Human))	BDBM40622 (MLS000053340 | N-(2-furanylmethyl)-2,3-dihydro-1H-...) Show SMILES O=C(NCc1ccco1)c1c2CCCc2nc2ccccc12 Show InChI InChI=1S/C18H16N2O2/c21-18(19-11-12-5-4-10-22-12)17-13-6-1-2-8-15(13)20-16-9-3-7-14(16)17/h1-2,4-6,8,10H,3,7,9,11H2,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	1.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (San Diego, CA) NIH Molecular Libraries Screening Cen...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q29C6VTK
					More data for this Ligand-Target Pair
Factor XIIa (Homo sapiens (Human))	BDBM40622 (MLS000053340 | N-(2-furanylmethyl)-2,3-dihydro-1H-...) Show SMILES O=C(NCc1ccco1)c1c2CCCc2nc2ccccc12 Show InChI InChI=1S/C18H16N2O2/c21-18(19-11-12-5-4-10-22-12)17-13-6-1-2-8-15(13)20-16-9-3-7-14(16)17/h1-2,4-6,8,10H,3,7,9,11H2,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q21G0JQS
					More data for this Ligand-Target Pair
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1 (Homo sapiens (Human))	BDBM40622 (MLS000053340 | N-(2-furanylmethyl)-2,3-dihydro-1H-...) Show SMILES O=C(NCc1ccco1)c1c2CCCc2nc2ccccc12 Show InChI InChI=1S/C18H16N2O2/c21-18(19-11-12-5-4-10-22-12)17-13-6-1-2-8-15(13)20-16-9-3-7-14(16)17/h1-2,4-6,8,10H,3,7,9,11H2,(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	5.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2V986KM
					More data for this Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM40622 (MLS000053340 | N-(2-furanylmethyl)-2,3-dihydro-1H-...) Show SMILES O=C(NCc1ccco1)c1c2CCCc2nc2ccccc12 Show InChI InChI=1S/C18H16N2O2/c21-18(19-11-12-5-4-10-22-12)17-13-6-1-2-8-15(13)20-16-9-3-7-14(16)17/h1-2,4-6,8,10H,3,7,9,11H2,(H,19,21)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	4.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2RJ4GWX
					More data for this Ligand-Target Pair
BZLF2 (Human herpesvirus 4 type 2)	BDBM40622 (MLS000053340 | N-(2-furanylmethyl)-2,3-dihydro-1H-...) Show SMILES O=C(NCc1ccco1)c1c2CCCc2nc2ccccc12 Show InChI InChI=1S/C18H16N2O2/c21-18(19-11-12-5-4-10-22-12)17-13-6-1-2-8-15(13)20-16-9-3-7-14(16)17/h1-2,4-6,8,10H,3,7,9,11H2,(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	1.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2057DCW
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM40622 (MLS000053340 | N-(2-furanylmethyl)-2,3-dihydro-1H-...) Show SMILES O=C(NCc1ccco1)c1c2CCCc2nc2ccccc12 Show InChI InChI=1S/C18H16N2O2/c21-18(19-11-12-5-4-10-22-12)17-13-6-1-2-8-15(13)20-16-9-3-7-14(16)17/h1-2,4-6,8,10H,3,7,9,11H2,(H,19,21)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	4.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q23X8539
					More data for this Ligand-Target Pair