BDBM430064 US10538528, Compound 12
SMILES: CCNCCNc1ccc(nc1C1CCN(CC1)c1ncnc2NC(=O)C(C)(C)c12)-c1cncc(F)c1
InChI Key: InChIKey=UQROQVVPXLGCTI-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM430064 (US10538528, Compound 12) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Taiho Pahrmaceutical Co., Ltd. US Patent | Assay Description S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass... | US Patent US10538528 (2020) BindingDB Entry DOI: 10.7270/Q2MK6G95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ryanodine receptor 1 [4317-4329] () | BDBM430064 (US10538528, Compound 12) | GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Taiho Pahrmaceutical Co., Ltd. US Patent | Assay Description Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass... | US Patent US10538528 (2020) BindingDB Entry DOI: 10.7270/Q2MK6G95 | |||||||||||
More data for this Ligand-Target Pair |